/* Synaptic Transmission 3D - Styles
 * Chemical synapse visualization with presynaptic terminal, cleft, and postsynaptic spine
 */

:root {
  --bg: #040812;
  --bg-2: #0a1220;
  --bg-3: #101a2e;
  --text: #e8f0f8;
  --muted: #7a94a8;
  --accent: #00e5ff;
  --accent-2: #ff9f43;
  --danger: #ff4757;
  --success: #2ed573;
  --warning: #ffa502;
  --purple: #a55eea;
  --pink: #ff6b9d;
  
  /* Presynaptic colors */
  --pre-primary: #ff6b6b;
  --pre-secondary: #ee5a5a;
  --pre-glow: rgba(255, 107, 107, 0.4);
  
  /* Postsynaptic colors */
  --post-primary: #4a9eff;
  --post-secondary: #3a8eef;
  --post-glow: rgba(74, 158, 255, 0.4);
  
  /* Molecular colors */
  --vesicle: #2ed573;
  --vesicle-fusing: #7bed9f;
  --glutamate: #ff6b6b;
  --gaba: #5f27cd;
  --calcium: #ffffff;
  --sodium: #ff4757;
  --potassium: #ffd93d;
  --chloride: #3867d6;
  --endocannabinoid: #2ed573;
  --astrocyte: #9980FA;
  
  /* Receptor colors */
  --ampa: #ff9f43;
  --nmda: #ee5a24;
  --gabaa: #5f27cd;
  --gabab: #833471;
  --cb1: #009432;
  --mglur: #ff6b9d;
}

* { box-sizing: border-box; margin: 0; padding: 0; }

body {
  font-family: 'SF Mono', 'Fira Code', 'JetBrains Mono', Monaco, monospace;
  background: radial-gradient(ellipse at 50% 0%, #0d1525 0%, var(--bg) 50%, #020408 100%);
  color: var(--text);
  overflow: hidden;
  height: 100vh;
}

#canvas-container {
  width: 100%;
  height: 100vh;
  position: relative;
  cursor: grab;
}

#canvas-container:active { cursor: grabbing; }

/* ============================================================================
   PANEL BASE STYLES
   ============================================================================ */

.info-panel {
  position: absolute;
  background: rgba(10, 18, 32, 0.95);
  border-radius: 14px;
  padding: 14px;
  backdrop-filter: blur(16px);
  box-shadow: 0 8px 32px rgba(0, 0, 0, 0.5), inset 0 1px 0 rgba(255, 255, 255, 0.05);
  font-size: 11px;
  z-index: 10;
}

.panel-title {
  font-size: 14px;
  font-weight: 700;
  margin-bottom: 2px;
  text-shadow: 0 0 12px currentColor;
}

.panel-subtitle {
  font-size: 9px;
  color: var(--muted);
  margin-bottom: 12px;
  letter-spacing: 0.5px;
  text-transform: uppercase;
}

/* ============================================================================
   PRESYNAPTIC PANEL (Top Left)
   ============================================================================ */

.presynaptic-panel {
  top: 60px;
  left: 20px;
  width: 260px;
  border: 1px solid rgba(255, 107, 107, 0.4);
}

.presynaptic-panel .panel-title {
  color: var(--pre-primary);
}

.voltage-section {
  margin-bottom: 12px;
  padding-bottom: 10px;
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
}

.voltage-label {
  font-size: 9px;
  color: var(--muted);
  margin-bottom: 4px;
  text-transform: uppercase;
  letter-spacing: 0.5px;
}

.voltage-display {
  font-size: 36px;
  font-weight: 700;
  color: var(--pre-primary);
  text-align: center;
  text-shadow: 0 0 20px var(--pre-glow);
  line-height: 1;
  margin-bottom: 6px;
}

.voltage-display .unit {
  font-size: 14px;
  opacity: 0.7;
}

.voltage-display.post {
  color: var(--post-primary);
  text-shadow: 0 0 20px var(--post-glow);
}

.voltage-bar {
  height: 6px;
  border-radius: 3px;
  position: relative;
  margin-bottom: 4px;
}

.voltage-bar.presynaptic {
  background: linear-gradient(90deg, 
    #3867d6 0%, 
    #2ed573 25%, 
    #ffd93d 50%, 
    #ff6b6b 75%, 
    #ff4757 100%
  );
}

.voltage-bar.postsynaptic {
  background: linear-gradient(90deg, 
    #5f27cd 0%, 
    #3867d6 25%, 
    #4a9eff 50%, 
    #ffd93d 75%, 
    #ff4757 100%
  );
}

.voltage-marker {
  position: absolute;
  top: -4px;
  width: 4px;
  height: 14px;
  background: white;
  border-radius: 2px;
  box-shadow: 0 0 8px white;
  transition: left 0.08s ease;
  left: 15%;
}

.phase-indicator {
  text-align: center;
  font-size: 10px;
  font-weight: 600;
  color: var(--success);
  text-transform: uppercase;
  letter-spacing: 1px;
}

.stats-section {
  margin-bottom: 10px;
}

.stat-row {
  display: flex;
  justify-content: space-between;
  font-size: 10px;
  padding: 3px 0;
  border-bottom: 1px solid rgba(255, 255, 255, 0.04);
}

.stat-label { color: var(--muted); }
.stat-value { color: var(--text); font-weight: 500; }

/* Vesicle Pools */
.vesicle-section {
  background: rgba(0, 0, 0, 0.3);
  border-radius: 8px;
  padding: 8px;
  margin-bottom: 10px;
}

.vesicle-title {
  font-size: 9px;
  color: var(--vesicle);
  text-transform: uppercase;
  letter-spacing: 1px;
  margin-bottom: 6px;
}

.vesicle-pool {
  display: flex;
  align-items: center;
  gap: 8px;
  margin: 4px 0;
}

.pool-bar {
  flex: 1;
  height: 8px;
  background: rgba(255, 255, 255, 0.1);
  border-radius: 4px;
  overflow: hidden;
}

.pool-fill {
  height: 100%;
  transition: width 0.3s ease;
  border-radius: 4px;
}

.pool-fill.rrp { background: linear-gradient(90deg, #ff6b6b, #ff9f43); }
.pool-fill.recycling { background: linear-gradient(90deg, #ffd93d, #2ed573); }
.pool-fill.reserve { background: linear-gradient(90deg, #4a9eff, #a55eea); }

.pool-label {
  font-size: 9px;
  color: var(--muted);
  min-width: 60px;
}

/* SNARE Indicator */
.snare-indicator {
  background: rgba(46, 213, 115, 0.1);
  border: 1px solid rgba(46, 213, 115, 0.3);
  border-radius: 8px;
  padding: 8px;
}

.snare-title {
  font-size: 9px;
  color: var(--vesicle);
  text-transform: uppercase;
  letter-spacing: 0.5px;
  margin-bottom: 6px;
}

.snare-status {
  display: flex;
  gap: 4px;
  margin-bottom: 6px;
}

.snare-component {
  flex: 1;
  padding: 3px 4px;
  font-size: 7px;
  text-align: center;
  border-radius: 3px;
  background: rgba(255, 255, 255, 0.1);
  transition: all 0.2s ease;
}

.snare-component.synaptobrevin { color: #ff6b6b; }
.snare-component.syntaxin { color: #ffd93d; }
.snare-component.snap25 { color: #4a9eff; }

.snare-component.active {
  background: rgba(46, 213, 115, 0.4);
  box-shadow: 0 0 8px rgba(46, 213, 115, 0.5);
}

.snare-state {
  font-size: 9px;
  text-align: center;
  color: var(--muted);
}

/* ============================================================================
   POSTSYNAPTIC PANEL (Top Right - positioned left of controls)
   ============================================================================ */

.postsynaptic-panel {
  top: 60px;
  right: 340px;
  width: 260px;
  border: 1px solid rgba(74, 158, 255, 0.4);
}

.postsynaptic-panel .panel-title {
  color: var(--post-primary);
}

/* PSP Indicators */
.psp-indicator {
  display: flex;
  gap: 10px;
  margin-bottom: 10px;
}

.psp-type {
  flex: 1;
  padding: 6px;
  text-align: center;
  border-radius: 6px;
  font-size: 10px;
  font-weight: 600;
}

.psp-type.epsp {
  background: rgba(255, 107, 107, 0.2);
  color: var(--danger);
  border: 1px solid rgba(255, 107, 107, 0.4);
}

.psp-type.ipsp {
  background: rgba(95, 39, 205, 0.2);
  color: var(--gabaa);
  border: 1px solid rgba(95, 39, 205, 0.4);
}

/* Receptor Sections */
.receptor-section {
  margin-bottom: 10px;
  padding: 8px;
  background: rgba(0, 0, 0, 0.2);
  border-radius: 6px;
}

.receptor-section.metabotropic {
  background: rgba(165, 94, 234, 0.1);
  border: 1px solid rgba(165, 94, 234, 0.2);
}

.receptor-title {
  font-size: 9px;
  color: var(--accent);
  text-transform: uppercase;
  letter-spacing: 0.5px;
  margin-bottom: 6px;
}

.receptor-row {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 3px 0;
  font-size: 9px;
}

.receptor-type {
  padding: 2px 6px;
  border-radius: 3px;
  font-weight: 600;
}

.receptor-type.ampa { background: rgba(255, 159, 67, 0.3); color: var(--ampa); }
.receptor-type.nmda { background: rgba(238, 90, 36, 0.3); color: var(--nmda); }
.receptor-type.gabaa { background: rgba(95, 39, 205, 0.3); color: var(--gabaa); }
.receptor-type.mglur { background: rgba(255, 107, 157, 0.3); color: var(--mglur); }
.receptor-type.gabab { background: rgba(131, 52, 113, 0.3); color: var(--gabab); }

.receptor-count {
  color: var(--muted);
}

.gprotein-indicator {
  margin-top: 6px;
  padding-top: 6px;
  border-top: 1px solid rgba(255, 255, 255, 0.1);
  font-size: 9px;
  display: flex;
  justify-content: space-between;
  color: var(--muted);
}

/* Synaptic Plasticity Mini Section (in receptor panel) */
.plasticity-section.plasticity-mini {
  background: rgba(155, 89, 182, 0.1);
  border: 1px solid rgba(155, 89, 182, 0.2);
  border-radius: 6px;
  padding: 8px;
  margin-bottom: 8px;
}

.plasticity-title {
  font-size: 9px;
  color: #a55eea;
  margin-bottom: 6px;
}

.plasticity-row {
  display: flex;
  justify-content: space-between;
  font-size: 9px;
  color: var(--muted);
  padding: 2px 0;
}

/* ============================================================================
   FLOATING PLASTICITY PANEL
   ============================================================================ */
.plasticity-panel {
  position: fixed;
  bottom: 20px;
  left: 50%;
  transform: translateX(-50%);
  width: 380px;
  background: rgba(15, 22, 36, 0.95);
  border: 2px solid #a55eea;
  border-radius: 12px;
  backdrop-filter: blur(10px);
  box-shadow: 0 8px 32px rgba(165, 94, 234, 0.3);
  z-index: 1000;
  overflow: hidden;
}

.plasticity-panel-header {
  background: linear-gradient(135deg, rgba(165, 94, 234, 0.3), rgba(155, 89, 182, 0.2));
  padding: 10px 15px;
  font-size: 13px;
  font-weight: 600;
  color: #a55eea;
  border-bottom: 1px solid rgba(165, 94, 234, 0.3);
}

.plasticity-content {
  padding: 12px 15px;
}

.plasticity-meter {
  margin-bottom: 12px;
}

.meter-label {
  font-size: 10px;
  color: var(--muted);
  margin-bottom: 4px;
}

.meter-bar-container {
  height: 20px;
  background: rgba(0, 0, 0, 0.4);
  border-radius: 4px;
  position: relative;
  overflow: hidden;
}

.meter-bar {
  height: 100%;
  border-radius: 4px;
  transition: width 0.2s ease, background 0.3s ease;
}

.ca-bar {
  background: linear-gradient(90deg, #3498db, #f1c40f, #e74c3c);
  width: 0%;
}

.ampa-bar {
  background: linear-gradient(90deg, #e74c3c, #f1c40f 50%, #2ecc71);
  width: 50%;
}

.ampa-container {
  background: linear-gradient(90deg, 
    rgba(231, 76, 60, 0.2) 0%, 
    rgba(0,0,0,0.4) 40%, 
    rgba(0,0,0,0.4) 60%, 
    rgba(46, 204, 113, 0.2) 100%
  );
}

.meter-baseline {
  position: absolute;
  left: 50%;
  top: 0;
  bottom: 0;
  width: 2px;
  background: white;
  opacity: 0.5;
}

.meter-threshold {
  position: absolute;
  top: 0;
  bottom: 0;
  width: 2px;
}

.ltp-threshold {
  left: 60%;
  background: #2ecc71;
  box-shadow: 0 0 4px #2ecc71;
}

.ltd-threshold {
  left: 30%;
  background: #e74c3c;
  box-shadow: 0 0 4px #e74c3c;
}

.meter-value {
  font-size: 12px;
  font-weight: 600;
  color: var(--accent);
  text-align: right;
  margin-top: 2px;
}

.plasticity-status {
  background: rgba(0, 0, 0, 0.3);
  border-radius: 6px;
  padding: 8px;
  margin-bottom: 10px;
}

.status-row {
  display: flex;
  justify-content: space-between;
  font-size: 10px;
  padding: 3px 0;
  color: var(--muted);
}

.status-value {
  font-weight: 600;
}

.plasticity-hint {
  font-size: 9px;
  color: var(--muted);
  background: rgba(165, 94, 234, 0.1);
  border-radius: 4px;
  padding: 8px;
  line-height: 1.5;
}

.plasticity-hint strong {
  color: #a55eea;
}

.pathway-section {
  background: rgba(0, 0, 0, 0.2);
  border-radius: 4px;
  padding: 6px 8px;
  margin: 6px 0;
  border-left: 2px solid #a55eea;
}

.pathway-title {
  font-size: 9px;
  color: #a55eea;
  margin-bottom: 4px;
  text-transform: uppercase;
  letter-spacing: 0.5px;
}

.highlight-row {
  background: rgba(165, 94, 234, 0.15);
  padding: 4px 6px;
  border-radius: 4px;
  margin-top: 6px;
}

.highlight-row span:last-child {
  font-size: 12px;
  font-weight: 700;
}

.plasticity-graphs {
  margin-top: 10px;
  background: rgba(0, 0, 0, 0.3);
  border-radius: 6px;
  padding: 8px;
}

.plasticity-graph-title {
  font-size: 9px;
  color: var(--muted);
  margin-bottom: 4px;
  text-transform: uppercase;
}

#plasticity-graph {
  width: 100%;
  height: 80px;
  background: rgba(0, 0, 0, 0.3);
  border-radius: 4px;
}

.plasticity-graph-legend {
  display: flex;
  justify-content: center;
  gap: 12px;
  margin-top: 4px;
}

.legend-item {
  font-size: 8px;
  color: var(--muted);
  display: flex;
  align-items: center;
  gap: 4px;
}

.legend-color {
  width: 10px;
  height: 3px;
  border-radius: 1px;
}

/* Endocannabinoid Section */
.endocannabinoid-section {
  background: rgba(46, 213, 115, 0.1);
  border: 1px solid rgba(46, 213, 115, 0.2);
  border-radius: 6px;
  padding: 8px;
}

.endo-title {
  font-size: 9px;
  color: var(--endocannabinoid);
  margin-bottom: 6px;
}

.endo-row {
  display: flex;
  justify-content: space-between;
  font-size: 9px;
  color: var(--muted);
  padding: 2px 0;
}

/* ============================================================================
   CLEFT PANEL (Bottom Left)
   ============================================================================ */

.cleft-panel {
  position: absolute;
  bottom: 20px;
  left: 20px;
  width: 240px;
  background: rgba(10, 18, 32, 0.95);
  border: 1px solid rgba(0, 229, 255, 0.3);
  border-radius: 12px;
  padding: 12px;
  backdrop-filter: blur(12px);
  font-size: 10px;
  z-index: 10;
}

.cleft-panel .panel-title {
  color: var(--accent);
  font-size: 12px;
  margin-bottom: 8px;
}

.cleft-info {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 4px 12px;
  margin-bottom: 10px;
  padding-bottom: 8px;
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
}

.cleft-stat {
  display: flex;
  justify-content: space-between;
  font-size: 9px;
}

.cleft-stat span:first-child { color: var(--muted); }
.cleft-stat span:last-child { color: var(--text); }

.clearance-section {
  background: rgba(0, 0, 0, 0.2);
  border-radius: 6px;
  padding: 8px;
}

.clearance-title {
  font-size: 8px;
  color: var(--accent);
  text-transform: uppercase;
  letter-spacing: 0.5px;
  margin-bottom: 6px;
}

.clearance-row {
  display: flex;
  justify-content: space-between;
  font-size: 8px;
  padding: 2px 0;
}

.clearance-type { color: var(--muted); }
.clearance-type.reuptake { color: #ffd93d; }
.clearance-type.enzymatic { color: #ff6b6b; }
.clearance-type.astrocyte { color: var(--astrocyte); }

/* ============================================================================
   LEGEND
   ============================================================================ */

.legend {
  position: absolute;
  bottom: 140px;
  left: 20px;
  background: rgba(10, 18, 32, 0.95);
  border: 1px solid rgba(0, 229, 255, 0.2);
  border-radius: 10px;
  padding: 10px;
  backdrop-filter: blur(12px);
  max-width: 240px;
  z-index: 10;
}

.legend-title {
  font-size: 9px;
  color: var(--accent);
  text-transform: uppercase;
  letter-spacing: 1px;
  margin-bottom: 8px;
}

.legend-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 3px 10px;
}

.legend-item {
  display: flex;
  align-items: center;
  font-size: 8px;
  color: var(--muted);
}

.legend-color {
  width: 10px;
  height: 10px;
  border-radius: 2px;
  margin-right: 5px;
  border: 1px solid rgba(255, 255, 255, 0.2);
}

.legend-color.vesicle { background: var(--vesicle); border-radius: 50%; }
.legend-color.glutamate { background: var(--glutamate); border-radius: 50%; }
.legend-color.gaba { background: var(--gaba); border-radius: 50%; }
.legend-color.calcium { background: var(--calcium); border-radius: 50%; }
.legend-color.sodium { background: var(--sodium); border-radius: 50%; }
.legend-color.potassium { background: var(--potassium); border-radius: 50%; }
.legend-color.chloride { background: var(--chloride); border-radius: 50%; }
.legend-color.endocannabinoid { background: var(--endocannabinoid); }
.legend-color.ampa-receptor { background: var(--ampa); }
.legend-color.nmda-receptor { background: var(--nmda); }
.legend-color.cb1-receptor { background: var(--cb1); }
.legend-color.astrocyte { background: var(--astrocyte); opacity: 0.7; }

/* ============================================================================
   CONTROLS PANEL (Right Side)
   ============================================================================ */

.controls-panel {
  position: absolute;
  top: 60px;
  right: 20px;
  width: 300px;
  background: rgba(10, 18, 32, 0.95);
  border: 1px solid rgba(0, 229, 255, 0.3);
  border-radius: 14px;
  padding: 16px;
  max-height: calc(100vh - 80px);
  overflow-y: auto;
  backdrop-filter: blur(12px);
  font-size: 11px;
  box-shadow: 0 8px 32px rgba(0, 0, 0, 0.5);
  z-index: 20;
}

.controls-panel::-webkit-scrollbar {
  width: 5px;
}

.controls-panel::-webkit-scrollbar-track {
  background: rgba(0, 0, 0, 0.2);
  border-radius: 3px;
}

.controls-panel::-webkit-scrollbar-thumb {
  background: rgba(0, 229, 255, 0.3);
  border-radius: 3px;
}

h2 {
  font-size: 12px;
  font-weight: 600;
  color: var(--accent);
  margin-bottom: 10px;
  padding-bottom: 6px;
  border-bottom: 1px solid rgba(0, 229, 255, 0.3);
}

.button-group {
  display: flex;
  gap: 6px;
  margin-bottom: 12px;
}

button {
  flex: 1;
  padding: 9px 8px;
  background: linear-gradient(135deg, rgba(0, 229, 255, 0.12), rgba(0, 229, 255, 0.04));
  border: 1px solid rgba(0, 229, 255, 0.35);
  border-radius: 6px;
  color: var(--text);
  cursor: pointer;
  font-size: 10px;
  font-weight: 600;
  font-family: inherit;
  transition: all 0.2s ease;
}

button:hover {
  background: linear-gradient(135deg, rgba(0, 229, 255, 0.22), rgba(0, 229, 255, 0.1));
  transform: translateY(-1px);
  box-shadow: 0 4px 12px rgba(0, 229, 255, 0.2);
}

button.active {
  background: linear-gradient(135deg, var(--success), rgba(46, 213, 115, 0.8));
  border-color: var(--success);
  box-shadow: 0 0 12px rgba(46, 213, 115, 0.4);
}

button.action-btn {
  background: linear-gradient(135deg, rgba(255, 71, 87, 0.2), rgba(255, 71, 87, 0.08));
  border-color: var(--danger);
}

button.action-btn:hover {
  background: linear-gradient(135deg, rgba(255, 71, 87, 0.35), rgba(255, 71, 87, 0.15));
}

button.train-btn {
  background: linear-gradient(135deg, rgba(255, 159, 67, 0.2), rgba(255, 159, 67, 0.08));
  border-color: var(--accent-2);
}

button.nt-btn {
  font-size: 9px;
}

#btn-reset-panels {
  background: linear-gradient(135deg, rgba(165, 94, 234, 0.15), rgba(165, 94, 234, 0.05));
  border-color: rgba(165, 94, 234, 0.5);
}

#btn-reset-panels:hover {
  background: linear-gradient(135deg, rgba(165, 94, 234, 0.25), rgba(165, 94, 234, 0.12));
}

button.nt-btn.active {
  background: linear-gradient(135deg, rgba(255, 107, 107, 0.4), rgba(255, 107, 107, 0.2));
  border-color: var(--glutamate);
}

.control-group {
  margin: 12px 0;
}

.control-label {
  display: flex;
  justify-content: space-between;
  align-items: center;
  margin-bottom: 5px;
  font-size: 10px;
}

.control-value {
  color: var(--accent);
  font-weight: 600;
}

input[type="range"] {
  width: 100%;
  height: 5px;
  border-radius: 3px;
  background: linear-gradient(90deg, var(--bg-3), var(--accent));
  outline: none;
  -webkit-appearance: none;
  appearance: none;
}

input[type="range"]::-webkit-slider-thumb {
  -webkit-appearance: none;
  appearance: none;
  width: 14px;
  height: 14px;
  border-radius: 50%;
  background: var(--accent);
  cursor: pointer;
  box-shadow: 0 0 6px rgba(0, 229, 255, 0.5);
  transition: transform 0.1s ease;
}

input[type="range"]::-webkit-slider-thumb:hover {
  transform: scale(1.15);
}

input[type="checkbox"] {
  width: 16px;
  height: 16px;
  cursor: pointer;
  accent-color: var(--accent);
}

.slider-hint {
  font-size: 8px;
  color: var(--muted);
  margin-top: 3px;
}

.section-divider {
  height: 1px;
  background: linear-gradient(90deg, transparent, rgba(0, 229, 255, 0.25), transparent);
  margin: 14px 0;
}

.visibility-hint {
  font-size: 9px;
  color: var(--muted);
  margin-bottom: 10px;
  font-style: italic;
  text-align: center;
}

.info-box {
  background: rgba(255, 159, 67, 0.08);
  border-left: 3px solid var(--accent-2);
  padding: 10px;
  margin: 12px 0;
  border-radius: 4px;
  font-size: 9px;
  line-height: 1.5;
  color: var(--muted);
}

.info-box strong {
  color: var(--accent-2);
}

.stats {
  font-size: 9px;
  color: var(--muted);
  margin-top: 12px;
  padding-top: 10px;
  border-top: 1px solid rgba(0, 229, 255, 0.15);
}

.stats div { margin: 3px 0; }

/* ============================================================================
   GRAPHS PANEL (Bottom Center-Right)
   ============================================================================ */

.graphs-panel {
  position: absolute;
  bottom: 20px;
  right: 340px;
  width: 300px;
  background: rgba(10, 18, 32, 0.95);
  border: 1px solid rgba(0, 229, 255, 0.2);
  border-radius: 12px;
  padding: 12px;
  backdrop-filter: blur(12px);
  z-index: 10;
}

.graph-container {
  margin-bottom: 10px;
}

.graph-container:last-child {
  margin-bottom: 0;
}

.graph-title {
  font-size: 9px;
  color: var(--accent);
  margin-bottom: 4px;
}

.graph-container canvas {
  width: 100%;
  height: 80px;
  background: rgba(0, 0, 0, 0.3);
  border-radius: 4px;
  border: 1px solid rgba(0, 229, 255, 0.15);
}

.graph-legend {
  display: flex;
  gap: 12px;
  margin-top: 3px;
  font-size: 8px;
}

.graph-legend-item {
  color: var(--muted);
}

.graph-legend-item.voltage { color: var(--pre-primary); }
.graph-legend-item.calcium { color: #ffffff; }
.graph-legend-item.psp { color: var(--post-primary); }
.graph-legend-item.threshold { color: var(--warning); }
.graph-legend-item.nt-conc { color: var(--glutamate); }
.graph-legend-item.binding { color: var(--ampa); }

/* Ion Flow Graph Legend */
.graph-legend-item.ion-net { color: #00ff88; }  /* Net flow - green */
.graph-legend-item.ion-na { color: #ff6b6b; }   /* Na+ influx - red/pink */
.graph-legend-item.ion-k { color: #ffd93d; }    /* K+ efflux - yellow */
.graph-legend-item.ion-cl { color: #4488ff; }   /* Cl- (GABA) - blue */

/* ============================================================================
   BACK LINK & HINTS
   ============================================================================ */

.back-link {
  position: absolute;
  top: 20px;
  left: 50%;
  transform: translateX(-50%);
  padding: 8px 20px;
  background: rgba(0, 229, 255, 0.1);
  border: 1px solid rgba(0, 229, 255, 0.3);
  border-radius: 20px;
  color: var(--accent);
  text-decoration: none;
  font-size: 11px;
  font-weight: 500;
  transition: all 0.2s ease;
  z-index: 100;
}

.back-link:hover {
  background: rgba(0, 229, 255, 0.2);
  box-shadow: 0 4px 16px rgba(0, 229, 255, 0.2);
}

.click-hint {
  position: absolute;
  bottom: 20px;
  left: 50%;
  transform: translateX(-50%);
  background: rgba(10, 18, 32, 0.9);
  padding: 10px 24px;
  border-radius: 20px;
  font-size: 10px;
  color: var(--muted);
  border: 1px solid rgba(0, 229, 255, 0.15);
  white-space: nowrap;
  z-index: 5;
}

/* ============================================================================
   DRAGGABLE PANEL SYSTEM
   ============================================================================ */

.draggable-panel {
  position: absolute;
  transition: box-shadow 0.2s ease;
}

.draggable-panel.dragging {
  cursor: grabbing !important;
  box-shadow: 0 16px 48px rgba(0, 0, 0, 0.6), 0 0 0 2px var(--accent);
  z-index: 1000 !important;
  transition: none;
}

/* Panel Header Wrapper */
.panel-header-wrapper {
  display: flex;
  align-items: center;
  gap: 8px;
  padding: 4px 4px 10px 4px;
  margin: -4px -4px 10px -4px;
  border-bottom: 1px solid rgba(255, 255, 255, 0.08);
  cursor: grab;
  user-select: none;
  border-radius: 12px 12px 0 0;
  background: linear-gradient(180deg, rgba(255, 255, 255, 0.03) 0%, transparent 100%);
}

.panel-header-wrapper:active {
  cursor: grabbing;
}

/* Drag Handle */
.panel-drag-handle {
  display: flex;
  align-items: center;
  justify-content: center;
  width: 16px;
  height: 20px;
  color: var(--muted);
  font-size: 10px;
  letter-spacing: -2px;
  opacity: 0.5;
  transition: opacity 0.2s ease, color 0.2s ease;
}

.panel-header-wrapper:hover .panel-drag-handle {
  opacity: 1;
  color: var(--accent);
}

/* Title Container */
.panel-title-container {
  flex: 1;
  min-width: 0;
}

.panel-title-container .panel-title {
  margin-bottom: 0;
}

.panel-title-container .panel-subtitle {
  margin-bottom: 0;
}

/* Minimize Button */
.panel-minimize-btn {
  flex-shrink: 0;
  width: 22px;
  height: 22px;
  padding: 0;
  display: flex;
  align-items: center;
  justify-content: center;
  background: rgba(255, 255, 255, 0.05);
  border: 1px solid rgba(255, 255, 255, 0.15);
  border-radius: 4px;
  color: var(--muted);
  font-size: 14px;
  font-weight: bold;
  line-height: 1;
  cursor: pointer;
  transition: all 0.15s ease;
}

.panel-minimize-btn:hover {
  background: rgba(0, 229, 255, 0.15);
  border-color: var(--accent);
  color: var(--accent);
  transform: none;
  box-shadow: none;
}

/* Minimized Panel State */
.draggable-panel.minimized {
  min-height: auto !important;
  max-height: none !important;
  height: auto !important;
  overflow: hidden;
}

.draggable-panel.minimized > *:not(.panel-header-wrapper) {
  display: none !important;
}

.draggable-panel.minimized .panel-header-wrapper {
  margin-bottom: 0;
  padding-bottom: 4px;
  border-bottom: none;
}

.draggable-panel.minimized .panel-title-container .panel-subtitle {
  display: none;
}

/* Specific panel minimized widths */
.presynaptic-panel.minimized,
.postsynaptic-panel.minimized {
  width: auto;
  min-width: 180px;
}

.cleft-panel.minimized,
.legend.minimized {
  width: auto;
  min-width: 140px;
}

.controls-panel.minimized {
  width: auto;
  min-width: 120px;
  max-height: none !important;
}

.graphs-panel.minimized {
  width: auto;
  min-width: 120px;
}

.plasticity-panel.minimized {
  width: auto;
  min-width: 200px;
}

/* Fix for plasticity panel - hide original content wrapper */
.plasticity-panel.minimized .plasticity-content {
  display: none !important;
}

/* Panel specific header colors */
.presynaptic-panel .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(255, 107, 107, 0.1) 0%, transparent 100%);
}

.postsynaptic-panel .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(74, 158, 255, 0.1) 0%, transparent 100%);
}

.cleft-panel .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(0, 229, 255, 0.1) 0%, transparent 100%);
}

.legend .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(0, 229, 255, 0.08) 0%, transparent 100%);
}

.controls-panel .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(0, 229, 255, 0.1) 0%, transparent 100%);
}

.graphs-panel .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(0, 229, 255, 0.08) 0%, transparent 100%);
}

.plasticity-panel .panel-header-wrapper {
  background: linear-gradient(180deg, rgba(165, 94, 234, 0.15) 0%, transparent 100%);
}

/* Hover effect for draggable panels */
.draggable-panel:hover {
  box-shadow: 0 8px 32px rgba(0, 0, 0, 0.5), inset 0 1px 0 rgba(255, 255, 255, 0.08);
}

/* Minimized panel hover shows expand hint */
.draggable-panel.minimized:hover .panel-minimize-btn {
  background: rgba(46, 213, 115, 0.2);
  border-color: var(--success);
  color: var(--success);
}

/* Grid snap visual indicator (shows during drag) */
.draggable-panel.dragging::before {
  content: '';
  position: fixed;
  top: 0;
  left: 0;
  right: 0;
  bottom: 0;
  pointer-events: none;
  background: 
    linear-gradient(rgba(0, 229, 255, 0.03) 1px, transparent 1px),
    linear-gradient(90deg, rgba(0, 229, 255, 0.03) 1px, transparent 1px);
  background-size: 20px 20px;
  z-index: -1;
}

/* ============================================================================
   ANIMATIONS
   ============================================================================ */

@keyframes pulse {
  0%, 100% { opacity: 1; transform: scale(1); }
  50% { opacity: 0.7; transform: scale(1.05); }
}

@keyframes glow {
  0%, 100% { box-shadow: 0 0 5px currentColor; }
  50% { box-shadow: 0 0 15px currentColor, 0 0 25px currentColor; }
}

@keyframes fusion {
  0% { transform: scale(1); opacity: 1; }
  50% { transform: scale(1.3); opacity: 0.8; }
  100% { transform: scale(0); opacity: 0; }
}

.vesicle-fusing {
  animation: fusion 0.3s ease-out forwards;
}

.channel-open {
  animation: glow 0.4s ease-in-out infinite;
}

.ap-active {
  animation: pulse 0.1s ease-in-out;
}

/* ============================================================================
   RESPONSIVE
   ============================================================================ */

@media (max-width: 1400px) {
  .postsynaptic-panel {
    right: 330px;
    width: 240px;
  }
  .graphs-panel {
    right: 330px;
    width: 280px;
  }
}

@media (max-width: 1200px) {
  .presynaptic-panel,
  .postsynaptic-panel {
    width: 220px;
    font-size: 10px;
  }
  .controls-panel {
    width: 260px;
  }
  .postsynaptic-panel {
    right: 290px;
  }
  .graphs-panel {
    display: none;
  }
}

@media (max-width: 1000px) {
  .presynaptic-panel {
    top: auto;
    bottom: 80px;
    left: 10px;
    width: 180px;
  }
  .postsynaptic-panel {
    display: none;
  }
  .cleft-panel {
    display: none;
  }
  .legend {
    display: none;
  }
  .controls-panel {
    width: 220px;
    right: 10px;
  }
}